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Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

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The nuclear magnetic resonance (NMR) spectroscopic data for organic macromolecules archived at the BioMagResBank (BMRB) present a wealthy useful resource of biophysical data at atomic decision. The NMR data archived in NMR-STAR ASCII format have been carried out in a relational database. However, it’s nonetheless pretty tough for customers to retrieve data from the NMR-STAR …

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Recent progress in the research of cold-inducible RNA-binding protein.

Recent progress in the research of cold-inducible RNA-binding protein.

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Cold-inducible RNA-binding protein (CIRP) is a cold-shock protein which will be induced after publicity to a reasonable cold-shock in totally different species starting from amphibians to people. Expression of CIRP may also be regulated by hypoxia, UV radiation, glucose deprivation, warmth stress and H2O2, suggesting that CIRP is a basic stress-response protein. In response to …

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A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson's disease potential biomarkers.

A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson’s disease potential biomarkers.

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The identification of circulating biomarkers that closely correlate with Parkinson’s Disease (PD) has failed several times in the past. Nevertheless, in this pilot study, a translational approach was conducted, allowing the evaluation of the plasma levels of two mitochondrial-related proteins, whose combination leads to a robust model with potential diagnostic value to discriminate the PD …

A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson’s disease potential biomarkers. Read More »

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