Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

The nuclear magnetic resonance (NMR) spectroscopic data for organic macromolecules archived at the BioMagResBank (BMRB) present a wealthy useful resource of biophysical data at atomic decision. The NMR data archived in NMR-STAR ASCII format have been carried out in a relational database. However, it’s nonetheless pretty tough for customers to retrieve data from the NMR-STAR information or the relational database in affiliation with data from different organic databases.

To improve the interoperability of the BMRB database, we current a full conversion of BMRB entries to two commonplace structured data codecs, XML and RDF, as frequent open representations of the NMR-STAR data. Moreover, a SPARQL endpoint has been deployed. The described case research demonstrates {that a} easy question of the SPARQL endpoints of the BMRB, UniProt, and Online Mendelian Inheritance in Man (OMIM), can be utilized in NMR and structure-based evaluation of proteins mixed with data of single nucleotide polymorphisms (SNPs) and their phenotypes.We have developed BMRB/XML and BMRB/RDF and reveal their use in performing a federated SPARQL question linking the BMRB to different databases by way of commonplace semantic web applied sciences. This will facilitate data alternate throughout various data assets.

Research in natural sciences is mainly done by means of experiments. Some of those experiments such as spaceflight-dependent experiments are extremely laborious, complex and expensive. Hence, they often remain rare events with little chances of statistical tests and possibilities of repetition. In order to make each single event as valuable as possible, a sophisticated comparison of experimental data received with the hundreds of millions of computer-stored documents appears necessary.

We used results of an earlier study on proteome analysis of microgravity-exposed human thyroid cancer cells, selected twenty proteins which appeared gravity sensitive and investigated whether their change observed in cells under the loss of gravity could cause health problems in astronauts. Using network analysis via Knowledge Explorer (KE) we searched the literature for diseases related to one or more of the selected proteins.

Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.
Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

After using Linked Open Data (LOD) and other public resources to establish a comprehensive semantic knowledgebase around functional properties of the selected proteins, the collection’s network was used to query a set of databases for the proteins’ involvement in biosystems and human diseases. Finally, possible countermeasures could be proposed.

Immunohistochemistry Kit (OKRA00039)

OKRA00039 1 kit
EUR 966
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

Immunohistochemistry Kit (OKRA00040)

OKRA00040 1 kit
EUR 966
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

DAB

HY-15912 500mg
EUR 129.6

Fmoc-Dab[Fmoc-Dab(Boc)]-OH

5-04727 5g Ask for price

Fmoc-Dab[Fmoc-Dab(Boc)]-OH

5-04728 25g Ask for price

DAB Tablet

D3225-020 20TB
EUR 170.4

DAB Tablet

D3225-050 50TB
EUR 295.2

H-Dab-OH·HCl

5-04703 5g Ask for price

H-Dab-OH·HCl

5-04704 25g Ask for price

Boc-Dab-OH

5-04711 5g Ask for price

Boc-Dab-OH

5-04712 25g Ask for price

Fmoc-Dab-OAll·HCl

5-04720 5g Ask for price

Fmoc-Dab-OH·HCl

5-04721 5g Ask for price

Fmoc-Dab-OH·HCl

5-04722 25g Ask for price

Fmoc-Dab-OH

5-04735 1g Ask for price

Fmoc-Dab-OH

5-04736 5g Ask for price

DAB Substrate kit

30015 1Kit
EUR 171.6
Description: Minimum order quantity: 1 unit of 1Kit

DAB Chromogen Kit

abx097197-1Kit 1 Kit
EUR 326.4

DL-Dab.2HCl

A6727-100000 100 g
EUR 682.8
Description: DL-Dab.2HCl

DL-Dab.2HCl

A6727-25000 25 g
EUR 370.8
Description: DL-Dab.2HCl

DL-Dab.2HCl

A6727-5000 5 g
EUR 216
Description: DL-Dab.2HCl

Boc-Dab-OH

A-3215.0001 1.0g
EUR 151.2
Description: Sum Formula: C9H18N2O4; CAS# [25691-37-6]

Boc-Dab-OH

A-3215.0005 5.0g
EUR 501.6
Description: Sum Formula: C9H18N2O4; CAS# [25691-37-6]

Boc-Dab-OH

A-3215.0025 25.0g
EUR 1893.6
Description: Sum Formula: C9H18N2O4; CAS# [25691-37-6]

Fmoc-Dab-OH

B-2300.0001 1.0g
EUR 181.2
Description: Sum Formula: C19H20N2O4; CAS# [161420-87-7]

Fmoc-Dab-OH

B-2300.0005 5.0g
EUR 618
Description: Sum Formula: C19H20N2O4; CAS# [161420-87-7]

DAB Chromogen Concentrate

D3226-002 20ml
EUR 193.2

DAB Chromogen Concentrate

D3226-005 50ml
EUR 400.8

DAB Differentiating Solution

DDS500 500 ml
EUR 130.8

Z-Dab-OH

C-3705.0001 1.0g
EUR 138
Description: Sum Formula: C12H16N2O4; CAS# [62234-40-6]

Z-Dab-OH

C-3705.0005 5.0g
EUR 327.6
Description: Sum Formula: C12H16N2O4; CAS# [62234-40-6]

Z-Dab-OH

C-3705.0025 25.0g
EUR 1197.6
Description: Sum Formula: C12H16N2O4; CAS# [62234-40-6]

DAB Chromogen Concentrate

ACB030 30 ml
EUR 142.8

DAB Chromogen Concentrate

ACB060 60 ml
EUR 198

DAB Chromogen Concentrate

ACB125 125 ml
EUR 294

DAB Chromogen Concentrate

ACB500 500 ml
EUR 805.2

DAB Chromogen Concentrate

ACB999 1000 ml
EUR 1390.8

DAB Substrate Buffer

ACC500 500 ml
EUR 86.4

DAB Substrate Buffer

ACC999 1000 ml
EUR 96

DAB Enhancer Solution

ACM030 30 ml
EUR 85.2

DAB Away Kit

ACP001 500 ml
EUR 117.6

DAB Chromogen, 4ml

NB314D 4 ml
EUR 295.2

H-Dab-OH

F-3050.0001 1.0g
EUR 138
Description: Sum Formula: C4H10N2O2; CAS# [1883-09-6]

H-Dab-OH

F-3050.0005 5.0g
EUR 270
Description: Sum Formula: C4H10N2O2; CAS# [1883-09-6]

H-Dab-OH

F-3050.0025 25.0g
EUR 963.6
Description: Sum Formula: C4H10N2O2; CAS# [1883-09-6]

DAB Enhancer for ampliying DAB stains in IHC staining, 60ml

NB308 60 ml
EUR 512.4

DAB Enhancer for ampliying DAB stains in IHC staining, 30ml

NB308-30 30 ml
EUR 358.8

H-Dab(Z)-OH

5-04707 5g Ask for price

H-Dab(Z)-OH

5-04708 25g Ask for price

Boc-Dab(Boc)-OH·DCHA

5-04713 1g Ask for price

Boc-Dab(Boc)-OH·DCHA

5-04714 5g Ask for price

Boc-Dab(Fmoc)-OH

5-04715 5g Ask for price

Boc-Dab(Fmoc)-OH

5-04716 25g Ask for price

Boc-Dab(Z)-OH·DCHA

5-04717 5g Ask for price

Boc-Dab(Z)-OH·DCHA

5-04718 25g Ask for price

Fmoc-Dab(Ac)-OH

5-04723 5g Ask for price

Fmoc-Dab(Ac)-OH

5-04724 25g Ask for price

Fmoc-Dab(Boc)-OH

5-04725 5g Ask for price

Fmoc-Dab(Boc)-OH

5-04726 25g Ask for price

Fmoc-Dab(Fmoc)-OH

5-04729 1g Ask for price

Fmoc-Dab(Fmoc)-OH

5-04730 5g Ask for price

Fmoc-Dab(MMt)-OH

5-04731 5g Ask for price

Fmoc-Dab(MMt)-OH

5-04732 25g Ask for price

Fmoc-Dab(Mtt)-OH

5-04733 1g Ask for price

Fmoc-Dab(Mtt)-OH

5-04734 5g Ask for price

Fmoc-Dab(Dde)-OH

5-04739 1g Ask for price

Fmoc-Dab(Dde)-OH

5-04740 5g Ask for price

Fmoc-Dab(ivDde)-OH

5-04741 1g Ask for price

Fmoc-Dab(ivDde)-OH

5-04742 5g Ask for price

Fmoc-Dab(Z)-OH

5-04743 1g Ask for price

Fmoc-Dab(Z)-OH

5-04744 5g Ask for price

Boc-D-Dab-OH

5-04745 1g Ask for price

Boc-D-Dab-OH

5-04746 5g Ask for price

Fmoc-D-Dab-OH

5-04751 1g Ask for price

Fmoc-D-Dab-OH

5-04752 5g Ask for price

10-DAB (10-Deacetylbaccatin)

A4395-25 25 mg
EUR 616.8
Description: 10-DAB (also known as 10-Deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the Pacific yew tree Taxus brevifolia as well as other species of the genus Taxus.

10-DAB (10-Deacetylbaccatin)

A4395-5 5 mg
EUR 199.2
Description: 10-DAB (also known as 10-Deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the Pacific yew tree Taxus brevifolia as well as other species of the genus Taxus.

10-DAB (10-Deacetylbaccatin)

A4395-5.1 10 mM (in 1mL DMSO)
EUR 351.6
Description: 10-DAB (also known as 10-Deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the Pacific yew tree Taxus brevifolia as well as other species of the genus Taxus.

10-DAB (10-Deacetylbaccatin)

A4395-S Evaluation Sample
EUR 97.2
Description: 10-DAB (also known as 10-Deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the Pacific yew tree Taxus brevifolia as well as other species of the genus Taxus.

Fmoc-Dab(Fmoc)-Oh

abx188721-250g 250 g
EUR 2064

H-Dab(Boc)-OH

A-3305.0001 1.0g
EUR 240
Description: Sum Formula: C9H18N2O4; CAS# [10270-94-7]

H-Dab(Boc)-OH

A-3305.0005 5.0g
EUR 835.2
Description: Sum Formula: C9H18N2O4; CAS# [10270-94-7]

Boc-Dab(Fmoc)-OH

A-3520.0001 1.0g
EUR 270
Description: Sum Formula: C24H28N2O6; CAS# [117106-21-5]

Boc-Dab(Fmoc)-OH

A-3520.0005 5.0g
EUR 936
Description: Sum Formula: C24H28N2O6; CAS# [117106-21-5]

Boc-Dab(Aloc)-OH

A-4125.0001 1.0g
EUR 370.8
Description: Sum Formula: C13H22N2O6; CAS# [171820-73-8]

Boc-Dab(Aloc)-OH

A-4125.0005 5.0g
EUR 1371.6
Description: Sum Formula: C13H22N2O6; CAS# [171820-73-8]

Boc-D-Dab-OH

A-4215.0001 1.0g
EUR 501.6
Description: Sum Formula: C9H18N2O4; CAS# [80445-78-9]

Boc-D-Dab-OH

A-4215.0005 5.0g
EUR 1864.8
Description: Sum Formula: C9H18N2O4; CAS# [80445-78-9]

Boc-Dab-OtBu · HCl

A-4415.0001 1.0g
EUR 370.8
Description: Sum Formula: C13H26N2O4·HCl; CAS# [190447-69-9] net

Boc-Dab-OtBu · HCl

A-4415.0005 5.0g
EUR 1371.6
Description: Sum Formula: C13H26N2O4·HCl; CAS# [190447-69-9] net

Fmoc-Dab(Boc)-OH

B-1800.0001 1.0g
EUR 240
Description: Sum Formula: C24H28N2O6; CAS# [125238-99-5]

Fmoc-Dab(Boc)-OH

B-1800.0005 5.0g
EUR 819.6
Description: Sum Formula: C24H28N2O6; CAS# [125238-99-5]

Fmoc-Dab(Fmoc)-OH

B-2270.0001 1.0g
EUR 283.2
Description: Sum Formula: C34H30N2O6; CAS# [201473-83-8]

Fmoc-Dab(Fmoc)-OH

B-2270.0005 5.0g
EUR 1039.2
Description: Sum Formula: C34H30N2O6; CAS# [201473-83-8]

Fmoc-D-Dab-OH

B-2365.0001 1.0g
EUR 501.6
Description: Sum Formula: C19H20N2O4; CAS# [201484-12-0]

Fmoc-D-Dab-OH

B-2365.0005 5.0g
EUR 1864.8
Description: Sum Formula: C19H20N2O4; CAS# [201484-12-0]

Fmoc-Dab(Aloc)-OH

B-2850.0001 1.0g
EUR 356.4
Description: Sum Formula: C23H24N2O6; CAS# [204316-32-5]

Fmoc-Dab(Aloc)-OH

B-2850.0005 5.0g
EUR 1327.2
Description: Sum Formula: C23H24N2O6; CAS# [204316-32-5]

Fmoc-Dab(Z)-OH

B-3250.0001 1.0g
EUR 313.2
Description: Sum Formula: C27H26N2O6; CAS# [252049-08-4]

Fmoc-Dab(Z)-OH

B-3250.0005 5.0g
EUR 1110
Description: Sum Formula: C27H26N2O6; CAS# [252049-08-4]

Fmoc-Dab(ivDde)-OH

B-4065.0001 1.0g
EUR 356.4
Description: Sum Formula: C32H38N2O6; CAS# [607366-21-2]

Fmoc-Dab(ivDde)-OH

B-4065.0005 5.0g
EUR 1311.6
Description: Sum Formula: C32H38N2O6; CAS# [607366-21-2]

DAB (Post) Enhancing Solution

DES500 500 ml
EUR 105.6

DAB (Post) Enhancing Solution

DES999 1000 ml
EUR 130.8

Z-Dab(Z)-OH

C-3690.0001 1.0g
EUR 240
Description: Sum Formula: C20H22N2O6; CAS# [55478-23-4]

Z-Dab(Z)-OH

C-3690.0005 5.0g
EUR 835.2
Description: Sum Formula: C20H22N2O6; CAS# [55478-23-4]

Z-D-Dab-OH

C-3770.0001 1.0g
EUR 270
Description: Sum Formula: C12H16N2O4; CAS# [70882-66-5]

Z-D-Dab-OH

C-3770.0005 5.0g
EUR 950.4
Description: Sum Formula: C12H16N2O4; CAS# [70882-66-5]

DAB Chromogen/Substrate Kit

ACH500 500 Slides
EUR 102

DAB Substrate (High Contrast)

ACU250 250 ml
EUR 102

DAB Substrate (High Contrast)

ACU500 500 ml
EUR 117.6

DAB Substrate (High Contrast)

ACU999 1000 ml
EUR 142.8

DAB Substrate buffer, 70ml

NB314SB 70 ml
EUR 331.2

Ac-Dab(Boc)-OH

F-1020.0250 250.0mg
EUR 283.2
Description: Sum Formula: C11H20N2O5; CAS# [201351-32-8]

Ac-Dab(Boc)-OH

F-1020.1000 1.0g
EUR 792
Description: Sum Formula: C11H20N2O5; CAS# [201351-32-8]

H-D-Dab-OH

F-3055.0001 1.0g
EUR 270
Description: Sum Formula: C4H10N2O2; CAS# [26908-94-1] net

H-D-Dab-OH

F-3055.0005 5.0g
EUR 950.4
Description: Sum Formula: C4H10N2O2; CAS# [26908-94-1] net

Sensitive DAB Stain Kit

PW023 5Preps, 5prep
EUR 82.97

Boc-D-Dab(Fmoc)-OH

5-04747 5g Ask for price

Boc-D-Dab(Fmoc)-OH

5-04748 25g Ask for price

Boc-D-Dab(Z)-OH·DCHA

5-04749 5g Ask for price

Boc-D-Dab(Z)-OH·DCHA

5-04750 25g Ask for price

Fmoc-D-Dab(Alloc)-OH

5-04753 1g Ask for price

Fmoc-D-Dab(Alloc)-OH

5-04754 5g Ask for price

Fmoc-D-Dab(Boc)-OH

5-04755 1g Ask for price

Fmoc-D-Dab(Boc)-OH

5-04756 5g Ask for price

Fmoc-D-Dab(Dde)-OH

5-04757 1g Ask for price

Fmoc-D-Dab(Dde)-OH

5-04758 5g Ask for price

Fmoc-D-Dab(MMt)-OH

5-04759 5g Ask for price

Fmoc-D-Dab(MMt)-OH

5-04760 25g Ask for price

Fmoc-D-Dab(Z)-OH

5-04761 250mg Ask for price

Fmoc-D-Dab(Z)-OH

5-04762 1g Ask for price

H-D-Dab-OH·2HCl

5-04763 5g Ask for price

H-D-Dab-OH·2HCl

5-04764 25g Ask for price

DAB Horseradish Peroxidase Chromogenic Kit

20-abx090660
  • EUR 276.00
  • EUR 226.80
  • 100 ml
  • 20 ml

H-D-Dab-OH.2HCl

A7493-1000 1 g
EUR 116.4
Description: H-D-Dab-OH?2HCl

H-D-Dab-OH.2HCl

A7493-25000 25 g
EUR 969.6
Description: H-D-Dab-OH?2HCl

H-D-Dab-OH.2HCl

A7493-5000 5 g
EUR 278.4
Description: H-D-Dab-OH?2HCl

Boc-Dab(Z)-OH · DCHA

A-2905.0001 1.0g
EUR 151.2
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [16947-89-0]

Boc-Dab(Z)-OH · DCHA

A-2905.0005 5.0g
EUR 471.6
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [16947-89-0]

Boc-Dab(Boc)-OH · DCHA

A-3480.0001 1.0g
EUR 211.2
Description: Sum Formula: C14H26N2O6·C12H23N; CAS# [201472-66-4]

Boc-Dab(Boc)-OH · DCHA

A-3480.0005 5.0g
EUR 704.4
Description: Sum Formula: C14H26N2O6·C12H23N; CAS# [201472-66-4]

Boc-D-Dab(Fmoc)-OH

A-4230.0001 1.0g
EUR 471.6
Description: Sum Formula: C24H28N2O6; CAS# [131570-57-5]

Boc-D-Dab(Fmoc)-OH

A-4230.0005 5.0g
EUR 1778.4
Description: Sum Formula: C24H28N2O6; CAS# [131570-57-5]

Fmoc-D-Dab(Boc)-OH

B-2960.0001 1.0g
EUR 471.6
Description: Sum Formula: C24H28N2O6; CAS# [114360-56-4]

Fmoc-D-Dab(Boc)-OH

B-2960.0005 5.0g
EUR 1778.4
Description: Sum Formula: C24H28N2O6; CAS# [114360-56-4]

DAB Chromogenic Substrate Kit (Brown)

AR1022 1 kit (for 600-900 assays)
EUR 96

DAB Chromogenic Substrate Kit (Blue)

AR1025 1 kit (for 600-900 assays)
EUR 96

Z-Dab(Boc)-OH · DCHA

C-3510.0001 1.0g
EUR 211.2
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [3350-13-8]

Z-Dab(Boc)-OH · DCHA

C-3510.0005 5.0g
EUR 704.4
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [3350-13-8]

DAB Chromogen/Substrate Bulk pack

ACK500 530 ml
EUR 144

DAB Chromogen/Substrate Bulk pack

ACK999 1060 ml
EUR 211.2

EconoTek HRP Anti-Polyvalent (DAB)

AEX080 70 Slides
EUR 159.6

H-Dab(Boc)-OMe · HCl

E-3360.0001 1.0g
EUR 270
Description: Sum Formula: C10H20N2O4·HCl; CAS# [3350-15-0]

H-Dab(Boc)-OMe · HCl

E-3360.0005 5.0g
EUR 950.4
Description: Sum Formula: C10H20N2O4·HCl; CAS# [3350-15-0]

H-Dab(Boc)-OMe · HCl

E-3360.0025 25.0g
EUR 3693.6
Description: Sum Formula: C10H20N2O4·HCl; CAS# [3350-15-0]

H-D-Dab(Boc)-OH

F-4200.0001 1.0g
EUR 283.2
Description: Sum Formula: C9H18N2O4; CAS# [114360-55-3]

H-D-Dab(Boc)-OH

F-4200.0005 5.0g
EUR 1023.6
Description: Sum Formula: C9H18N2O4; CAS# [114360-55-3]

7,10-Dimethoxy-10-DAB III

TBZ3002 20mg Ask for price

Boc-D-Dab(Z)-OH · DCHA

A-4260.0001 1.0g
EUR 400.8
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [101854-42-6]

Boc-D-Dab(Z)-OH · DCHA

A-4260.0005 5.0g
EUR 1488
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [101854-42-6]

3,3-Diaminobenzidine (DAB) 5mg Substrate Tabs

CH027 50 Tabs
EUR 212.4

3,3-Diaminobenzidine (DAB) 5mg Substrate Tabs

CH028 100 Tabs
EUR 279.6

Z-D-Dab(Boc)-OH · DCHA

C-3765.0001 1.0g
EUR 457.2
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [214852-61-6]

Z-D-Dab(Boc)-OH · DCHA

C-3765.0005 5.0g
EUR 1705.2
Description: Sum Formula: C17H24N2O6·C12H23N; CAS# [214852-61-6]

DAB Chromogen/Substrate Kit (High Contrast)

ACT500 500 Slides
EUR 188.4

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